Simulation-free magnetic resonance-guided radiation therapy of prostate cancer.

ABSTRACT:

Background and purpose

Despite recent advances of online image-guided high-precision patient positioning and adaptation using magnetic resonance imaging (MRI) or cone-beam computed tomography (CT), standard radiation therapy pathway still involves a dedicated simulation scan. The aim of this study was to evaluate the feasibility and planning quality of integrating a simulation-free treatment planning workflow for adaptive online MRI-guided radiation therapy on a 1.5 T MRI linear accelerator (MRI-Linac) in prostate cancer using diagnostic CT (dCT) scans.

Materials and methods

For ten patients with prostate cancer previously treated at the MRI-Linac with adaptive radiation therapy (42.7 Gy in 7 fractions), simulation-free reference plans based on dCT were retrospectively creat

SUBMITTER: Warda C 

PROVIDER: S-EPMC11609320 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature