Deciphering the genomic character of the multidrug-resistant Staphylococcus aureus from Dhaka, Bangladesh.

ABSTRACT: Staphylococcus aureus is one of the leading agents of nosocomial and community-acquired infections. In this study, we explored the genomic characterization of eight methicillin-resistant clinical isolates of S. aureus from Dhaka, Bangladesh. Notably, all strains were resistant to penicillin, cephalosporins, and monobactams, with partial susceptibility to meropenem and complete susceptibility to amikacin, vancomycin, and tigecycline antibiotics. The strains were found to have an average genome size of 2.73 Mbp and an average of 32.64% GC content. Multi-locus sequence typing analysis characterized the most predominant sequence type as ST361, which belongs to the clonal complex CC361. All isolates harbored the mecA gene, often linked to SCCmec_type IV variants. Mul

SUBMITTER: Anjum A 

PROVIDER: S-EPMC11609420 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature