Dose-effect relationship in external beam radiotherapy combined with brachytherapy for cervical cancer: A systematic review.

ABSTRACT:

Purpose

External beam radiotherapy with concurrent chemotherapy combined with brachytherapy has been described as the first treatment choice for locally advanced cervical cancer. This study aimed to systematically review the dose-effect relationship (DER) of target volumes and organs at risk (OARs) in external beam radiotherapy combined with brachytherapy for cervical cancer.

Material and methods

Studies reporting DER in radical radiotherapy for cervical cancer were determined by searching PubMed, Web of Science, and Cochrane Library databases till Jan 20, 2023. Dose parameters of DER, end-point of tumor control or type and grade of side effects of OARs as well as prediction results were analyzed from included studies. Coordinates of DER curves from the included studies were

SUBMITTER: Wu N 

PROVIDER: S-EPMC11609865 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature