Evaluation of cardiac findings using speckle-tracking echocardiography in fetuses with hemoglobin Bart's disease.

ABSTRACT:

Objective

Hemoglobin (Hb) Bart's disease is a severe manifestation of alpha-thalassemia, resulting in fetal tissue hypoxia and severe anemia. There is limited research available on assessing speckle-tracking analysis of the fetal heart as a response to fetal anemia caused by Hb Bart's disease. This study aimed to assess the diagnostic performance of fetal cardiac measurements derived from speckle-tracking analysis to identify fetuses with Bart's anemia between 17 and 24 weeks of gestation.

Methods

This prospective cohort study included 115 women with singleton pregnancies at risk for fetal Hb Bart's disease who underwent either amniocentesis or cordocentesis at Siriraj Hospital, Bangkok, Thailand, in the period between January 2019 and January 2021. Speckle-tracking analysis

SUBMITTER: Anuwutnavin S 

PROVIDER: S-EPMC11609887 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature