Advancing the role of real-world evidence in comparative effectiveness research.

ABSTRACT: Aim: Comparative effectiveness research (CER) is essential for making informed decisions about drug access. It provides insights into the effectiveness and safety of new drugs compared with existing treatments, thereby guiding better healthcare decisions and ensuring that new therapies meet the real-world needs of patients and healthcare systems. Objective: To provide a tool that assists analysts and decision-makers in identifying the most suitable analytical approach for answering a CER question, given specific data availability contexts. Methods: A systematic literature review of the scientific literature was performed and existing regulatory and health technology assessment (HTA) guidance were evaluated to identify and compare recommendations and best practices. Bas

SUBMITTER: Daigl M 

PROVIDER: S-EPMC11609978 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature