Characteristics of gut microbiota of premature infants in the early postnatal period and their relationship with intraventricular hemorrhage.

ABSTRACT:

Background

Studies have shown correlations between gut microbiota and neurocognitive function, but little was known about the early postnatal gut microbiota and intraventricular hemorrhage (IVH). We aimed to explore the characteristics of gut microbiota in premature infants and their relationship with IVH, further exploring potential therapeutic targets.

Methods

Premature infants delivered at Peking University First Hospital from February 2023 to August 2023 were recruited as a cohort. Feces samples were collected on postnatal days 1, 3, and 5. Premature infants were divided into normal, mild IVH, and severe IVH groups based on cranial ultrasound. 16S rRNA amplicon sequencing technology was used to determine the fecal microbiota, and the results were analyzed.

Results

SUBMITTER: Zhao Y 

PROVIDER: S-EPMC11610090 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature