Transcriptomic analysis of regulatory mechanisms in the telogen-anagen transition of ovine hair follicles.

ABSTRACT:

Background

Dorper sheep are celebrated for their fast maturation and superior meat quality, with some shedding their wool each spring. Wool shedding occurs naturally due to the hair follicle (HF) cycle, but its regulatory mechanisms remain unclear and need further investigation.

Results

In this study, shedding and non-shedding sheep were selected from the same Dorper flock. Skin samples were collected in September of the first year and January and March of the following years. RNA sequencing was performed on these samples. Principal component analysis (PCA) was used to assess the results. A total of 2536 differentially expressed genes (DEGs) were identified. Using a clustering heatmap and fuzzy clustering analysis three distinct gene expression patterns were identified: A pa

SUBMITTER: Zhang N 

PROVIDER: S-EPMC11610194 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature