Left atrial dysfunction relates to symptom onset in patients affected by severe degenerative mitral regurgitation.

ABSTRACT:

Background

Left atrium (LA) is far from simply being a passive connection chamber between left ventricle and the pulmonary circulation. In patients affected by mitral regurgitation (MR) an impairment in LA compliance and reservoir function, which can be evaluated using Speckle Tracking echocardiography, lead to elevated atrial pressure, resulting in increased pulmonary capillary pressures and the onset of dyspnea. Our study aims to evaluate the correlation between left atrial dysfunction and symptoms onset in patients with severe degenerative MR. Identifying left atrial dysfunction as a predictor of symptoms could be helpful to guide management strategy of asymptomatic patients with severe degenerative MR.

Methods

In a retrospective analysis, we examined all patients diagnos

SUBMITTER: Ingallina G 

PROVIDER: S-EPMC11610303 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature