Distribution of Clostridioides difficile ribotypes and sequence types across humans, animals and food in 13 European countries.

ABSTRACT: Clostridioides difficile is a One Health pathogen found in humans, animals, and the environment, with food representing a potential transmission route. One Health studies are often limited to a single country or selected reservoirs and ribotypes. This study provides a varied and accessible collection of C. difficile isolates and sequencing data derived from human, animal, and food sources across 13 European countries. A total of 441 strains (human hospital- and community-associated cases n = 280, animal n = 96, food n = 65) were analysed by ribotyping, toxinotyping and whole-genome sequencing (WGS). We detected 83 sequence types (STs), with ST11 (n = 80 isolates) and ST1 (n = 54 isolates) being the most represented. Several STs included stra

SUBMITTER: Rupnik M 

PROVIDER: S-EPMC11610360 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature