Chromosome-level subgenome-aware de novo assembly provides insight into <i>Saccharomyces bayanus</i> genome divergence after hybridization.

ABSTRACT: Interspecies hybridization is prevalent in various eukaryotic lineages and plays important roles in phenotypic diversification, adaptation, and speciation. To better understand the changes that occurred in the different subgenomes of a hybrid species and how they facilitate adaptation, we have completed chromosome-level de novo assemblies of all chromosomes for a recently formed hybrid yeast, Saccharomyces bayanus strain CBS380, using Oxford Nanopore Technologies' MinION long-read sequencing. We characterize the S. bayanus genome and compare it with its parent species, Saccharomyces uvarum and Saccharomyces eubayanus, and other S. bayanus genomes to better understand genome evolution after a relatively recent hybridization event. We observe multiple recom

SUBMITTER: Gardner C 

PROVIDER: S-EPMC11610598 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature