Antimicrobial efficacy of chitosan versus sodium hypochlorite: A systematic review and meta-analysis.

ABSTRACT:

Aim

This meta-analysis aimed to compare the antibacterial efficacy of chitosan/chitosan nanoparticles (Ch/Ch-NPs) versus sodium hypochlorite/chlorhexidine (NaOCl/CHX).

Materials and methods

A search was performed in four electronic databases until December 08, 2023. Studies with missing, unclear, and insufficient data sets were excluded. The included studies were assessed by two independent reviewers using the Joanna Briggs Institute Critical Appraisal Checklist for Quasi-Experimental Studies. The meta-analysis of standardized mean difference was performed using a random effects model. Additionally, funnel plots as well as Egger's regression intercept test were used to evaluate potential publication bias.

Results

A total of 426 samples were used in nine included studi

SUBMITTER: Cakici F 

PROVIDER: S-EPMC11610686 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature