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Prognostic importance of extensive coronary calcium on lung cancer screening chest computed tomography.


ABSTRACT:

Background

Low-dose chest computed tomography (CT) is used for lung cancer screening, but can also detect coronary artery disease as coronary artery calcium. We sought to determine the prevalence and prognostic utility of coronary artery calcium in a population at high risk of cancer.

Methods

We reviewed CT scans from consecutive participants screened for lung cancer between March 2017 and November 2018 as part of the Ontario Health Lung Cancer Screening Pilot for People at High Risk. We quantified coronary artery calcium using an estimated Agatston score. We identified the composite primary outcome of all-cause death and cardiovascular events using linked electronic medical record data from The Ottawa Hospital to December 2023.

Results

Among 1486 people who underwent

SUBMITTER: Caires MC 

PROVIDER: S-EPMC11611381 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature