Short-term changes in brain networks and cognition in children with frontal lobe lesions treated solely with neurosurgical procedures.

ABSTRACT: Intracranial lesions in children often have good prognoses, allowing long-term survival. Cognitive functions, crucial for life quality, need more attention. Previous research has focused on adults, with pediatric studies limited by varied lesions and complex treatments. This study aims to evaluate cognitive and brain network changes in children with frontal lobe lesions, which significantly impact cognitive function, using a before-and-after comparison. The study enrolled 20 children with frontal lesions who underwent fMRI and cognitive tests before and after surgery, with only surgical treatment initially. Brain network changes were evaluated using functional metrics, and cognitive shifts were measured through test scores. Correlations were analyzed to explore brain mechanisms behind cogn

SUBMITTER: Guan X 

PROVIDER: S-EPMC11611908 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature