Unveiling the cell dynamics during the final shape formation of the tarsus in Drosophila adult leg by live imaging.

ABSTRACT: Organisms display a remarkable diversity in their shapes. Although substantial progress has been made in unraveling the mechanisms that govern cell fate determination during development, the mechanisms by which fate-determined cells give rise to the final shapes of organisms remain largely unknown. This study describes in detail the process of the final shape formation of the tarsus, which is near the distal tip of the adult leg, during the pupal stage in Drosophila melanogaster. Days-long live imaging revealed unexpectedly complicated cellular dynamics. The epithelial cells transiently form the intriguing structure, which we named the Parthenon-like structure. The basal surface of the epithelial cells and localization of the basement membrane protein initially show a mesh-like structure a

SUBMITTER: Hiraiwa S 

PROVIDER: S-EPMC11611951 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature