Iron changes within infarct tissue in ischemic stroke patients after successful reperfusion quantified using QSM.

ABSTRACT:

Purpose

For nearly half of patients who undergo Endovascular Thrombectomy following ischemic stroke, successful recanalisation does not guarantee a good outcome. Understanding the underlying tissue changes in the infarct tissue with the help of biomarkers specific to ischemic stroke could offer valuable insights for better treatment and patient management decisions. Using quantitative susceptibility mapping (QSM) MRI to measure cerebral iron concentration, this study aims to track the progression of iron within the infarct lesion after successful reperfusion.

Methods

In a prospective study of 87 ischemic stroke patients, successfully reperfused patients underwent MRI scans at 24-to-72 h and 3 months after reperfusion. QSM maps were generated from gradient-echo MRI images. QS

SUBMITTER: Kataike VM 

PROVIDER: S-EPMC11611990 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature