A preliminary study of white matter disconnections underlying deficits in praxis in left hemisphere stroke patients.

ABSTRACT: Limb apraxia is a higher-order motor disorder often occurring post-stroke, which affects skilled actions. It is assessed through tasks involving gesture production or pantomime, recognition, meaningless gesture imitation, complex figure drawing, single and multi-object use. A two-system model for the organisation of actions hypothesizes distinct pathways mediating praxis deficits via conceptual, 'indirect', and perceptual 'direct' routes to action. Traditional lesion- symptom mapping techniques have failed to identify these distinct routes. We assessed 29 left hemisphere stroke patients to investigate white matter disconnections on deficits of praxis tasks from the Birmingham Cognitive Screening. White matter disconnection maps derived from patients' structural T1 lesions were created usin

SUBMITTER: Rounis E 

PROVIDER: S-EPMC11611995 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature