Radiomics Nomogram Derived from Gated Myocardial Perfusion SPECT for Identifying Ischemic Cardiomyopathy.

ABSTRACT: Personalized management involving heart failure (HF) etiology is crucial for better prognoses. We aim to evaluate the utility of a radiomics nomogram based on gated myocardial perfusion imaging (GMPI) in distinguishing ischemic from non-ischemic origins of HF. A total of 172 heart failure patients with reduced left ventricular ejection fraction (HFrEF) who underwent GMPI scan were divided into training (n = 122) and validation sets (n = 50) based on chronological order of scans. Radiomics features were extracted from the resting GMPI. Four machine learning algorithms were used to construct radiomics models, and the model with the best performances were selected to calculate the Radscore. A radiomics nomogram was constructed based on the Radscore and independent clinical factors. Finally, t

SUBMITTER: Zhou C 

PROVIDER: S-EPMC11612043 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature