Development and validation of a nomogram for predicting survival in gastric signet ring cell carcinoma patients treated with radiotherapy.

ABSTRACT: There is no effective clinical prediction model to predict the prognosis of gastric signet ring cell carcinoma (GSRC) patients treated with radiotherapy. This study retrospectively analyzed the clinical data of 20-80-year-old patients diagnosed with GSRC between 2004 and 2019 from the Surveillance, Epidemiology, and End Results (SEER) database. Using Cox regression analyses revealed independent prognostic factors, and a nomogram was constructed. The C-index, net reclassification index (NRI) and integrated discrimination improvement (IDI) of the nomogram were greater than those of the TNM staging system for predicting OS, indicating that the nomogram predicted prognosis with greater accuracy. The area under the curve (AUC) values were 0.725, 0.753 and 0.745 for the training group; 0.725, 0.

SUBMITTER: Wan G 

PROVIDER: S-EPMC11612298 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature