Early administration of anamorelin improves cancer cachexia in gastrointestinal cancer patients: an observational study.

ABSTRACT: To report the efficacy of anamorelin in patients with colorectal and gastric cancer with cachexia and in those receiving systemic chemotherapy. We retrospectively collected real-world data from patients diagnosed with colorectal and gastric cancers experiencing cachexia who were treated with anamorelin. We evaluated the efficacy of treatment by measuring the improvements in appetite and body weight (BW) gain. Between June 2021 and October 2022, 43 cancer patients with cachexia-23 with gastric cancer and 20 with colorectal cancer-were treated with anamorelin. Median observation period was 7.3 months. The participants were 25 males with median age of 71 years and median BMI of 19.7. The ECOG PS distribution was 4, 33, 6 for grades 0, 1, and 2, respectively. Seven patients received supportive

SUBMITTER: Matsumoto T 

PROVIDER: S-EPMC11612480 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature