Enhancing Frailty Assessments for Transcatheter Aortic Valve Replacement Patients Using Structured and Unstructured Data: Real-World Evidence Study.

ABSTRACT:

Background

Transcatheter aortic valve replacement (TAVR) is a commonly used treatment for severe aortic stenosis. As degenerative aortic stenosis is primarily a disease afflicting older adults, a frailty assessment is essential to patient selection and optimal periprocedural outcomes.

Objective

This study aimed to enhance frailty assessments of TAVR candidates by integrating real-world structured and unstructured data.

Methods

This study analyzed data from 14,000 patients between January 2018 and December 2019 to assess frailty in TAVR patients at the University of Florida. Frailty was identified using the Fried criteria, which includes weight loss, exhaustion, walking speed, grip strength, and physical activity. Latent Dirichlet allocation for topic modeling and Extr

SUBMITTER: Mardini MT 

PROVIDER: S-EPMC11612520 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature