Free-breathing non-contrast T1ρ dispersion magnetic resonance imaging of myocardial interstitial fibrosis in comparison with extracellular volume fraction.

ABSTRACT:

Background

Myocardial fibrosis is a common feature in various cardiac diseases. It causes adverse cardiac remodeling and is associated with poor clinical outcomes. Late gadolinium enhancement (LGE) and extracellular volume fraction (ECV) are the standard magnetic resonance imaging techniques for detecting focal and diffuse myocardial fibrosis. However, these contrast-enhanced techniques require the administration of gadolinium contrast agents, which is not applicable to patients with gadolinium contraindications. To eliminate the need for contrast agents, we developed and applied an endogenous free-breathing T1ρ dispersion imaging technique (FB-MultiMap) for diagnosing diffuse myocardial fibrosis in a cohort with suspected cardiomyopathies.

Methods

The proposed FB-MultiMap t

SUBMITTER: Miao Q 

PROVIDER: S-EPMC11612770 | biostudies-literature | 2024 Winter

REPOSITORIES: biostudies-literature