Risk factors of hepatocellular carcinoma associated with nonalcoholic fatty liver disease: Systematic review and meta-analysis.

ABSTRACT:

Background

Nonalcoholic fatty liver disease (NAFLD) is currently an important chronic liver disease threatening human life and health.

Objective

To investigate the risk factors of hepatocellular carcinoma (HCC) associated with nonalcoholic fatty liver disease (NAFLD) by systematic review.

Methods

We conducted a systematic review and meta-analysis. A systematic search of Chinese and English databases (PubMed, Web of Science, Cochrane Library, China national knowledge infrastructure (CNKI), Wanfang database, and VIP database) was performed until June 30, 2023. Studies were included to investigate the risk factors for HCC in patients with NAFLD. Quality evaluation was performed using the Newcastle-Ottawa Literature Quality Evaluation Scale, and then hazard ratios (HRs) f

SUBMITTER: Yin H 

PROVIDER: S-EPMC11613056 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature