Electroencephalography derived connectivity informing epilepsy surgical planning: Towards clinical applications and future perspectives.

ABSTRACT: Epilepsy is one of the most diffused neurological disorders, affecting 50 million people worldwide. Around 30% of patients have drug-resistant epilepsy (DRE), defined as failure of at least two tolerated antiseizure medications (ASMs) to achieve sustained seizure freedom. Brain surgery is an effective therapeutic approach in this group, hinging on the accurate localization of the epileptic focus. The latter task is complex and requires multimodal investigation methods. Epilepsy is also a network disorder and represents one of the best application scenarios of methods leveraging brain functional organization at large scales. Connectivity analysis represents a promising tool for improving surgical assessment, enabling better identification of candidates who could benefit the most from epilep

SUBMITTER: Salvatici G 

PROVIDER: S-EPMC11613172 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature