Deep learning-based hyperspectral image correction and unmixing for brain tumor surgery.

ABSTRACT: Hyperspectral imaging for fluorescence-guided brain tumor resection improves visualization of tissue differences, which can ameliorate patient outcomes. However, current methods do not effectively correct for heterogeneous optical and geometric tissue properties, leading to less accurate results. We propose two deep learning models for correction and unmixing that can capture these effects. While one is trained with protoporphyrin IX (PpIX) concentration labels, the other is semi-supervised. The models were evaluated on phantom and pig brain data with known PpIX concentration; the supervised and semi-supervised models achieved Pearson correlation coefficients (phantom, pig brain) between known and computed PpIX concentrations of (0.997, 0.990) and (0.98, 0.91), respectively. The classical

SUBMITTER: Black D 

PROVIDER: S-EPMC11613202 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature