Adolescent brain maturation associated with environmental factors: a multivariate analysis.

ABSTRACT: Human adolescence marks a crucial phase of extensive brain development, highly susceptible to environmental influences. Employing brain age estimation to assess individual brain aging, we categorized individuals (N = 7,435, aged 9-10 years old) from the Adolescent Brain and Cognitive Development (ABCD) cohort into groups exhibiting either accelerated or delayed brain maturation, where the accelerated group also displayed increased cognitive performance compared to their delayed counterparts. A 4-way multi-set canonical correlation analysis integrating three modalities of brain metrics (gray matter density, brain morphological measures, and functional network connectivity) with nine environmental factors unveiled a significant 4-way canonical correlation between linked patterns of ne

SUBMITTER: Ray B 

PROVIDER: S-EPMC11613425 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature