Association between alpha blocker use and the risk of fractures in patients with chronic kidney disease: a cohort study.

ABSTRACT:

Background

Alpha blockers (ABs) are frequently prescribed to patients with chronic kidney disease (CKD), which is often complicated by refractory hypertension (HT). Although there have been several reports on the association between AB use and the risk of fractures, their conclusions have not yet been drawn. Therefore, this study aimed to investigate the association between AB use and the risk of fractures in patients with CKD.

Method

This population-based cohort study used patient data obtained between April 2008 and August 2021 from a large-scale Japanese medical claims database. Consecutive patients with CKD who were newly prescribed ABs or non-AB antihypertensive drugs were included; males and females were analysed separately. The AB group was then divided into AB for HT

SUBMITTER: Sunohara K 

PROVIDER: S-EPMC11613485 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature