Returning actionable genetic results to participants in the biobank at the Colorado Center for Personalized Medicine and UCHealth.

ABSTRACT:

Purpose

To describe our process for returning genetic results to participants in the Colorado Center for Personalized Medicine biobank.

Methods

Enrollment in the biobank is open to all adult UCHealth patients. Participants who provided a sample that was genotyped and signed the proper consent were eligible to receive results. Genetic data were generated using a custom genotyping array and confirmed via Sanger sequencing. We used 2 models for returning results and conducted interviews with participants to assess satisfaction with our process, follow-up care, and family communication.

Results

As of July 2022, 73,313 participants had provided a sample and proper consent. Of these, 10,489 samples were genotyped, 137 (1.3%) had initial results, and 62 were confirmed and el

SUBMITTER: Lowery JT 

PROVIDER: S-EPMC11613693 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature