Factors affecting couples' decision making about expanded prenatal cell-free DNA screening.

ABSTRACT:

Purpose

To assess intended parents' preferences about expanded prenatal cell-free DNA screening.

Methods

A survey was administered to couples who were pregnant or trying to conceive. Partners within couples were independently asked about willingness to seek prenatal cell-free DNA screening for diseases and traits that varied by severity, treatability, age of onset, and reliability. Additional questions explored couples' decision-making processes and how various factors would affect those decisions.

Results

Respondents (n = 494) were most likely to seek a prenatal genetic test when the test is completely predictive (P value of predictability effect = .0116), for earlier onset (P value of onset effect = .0310), treatable diseases (P value of

SUBMITTER: Mumford K 

PROVIDER: S-EPMC11613822 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature