Experimental evolution reveals evolutionary bias and its causes.

ABSTRACT:

Background

Species generally exhibits evolutionary bias, adapting towards a specific direction rather than others, yet the underlying causes remains unknown.

Results

Here, we investigated evolutionary bias and its causes by conducting experimental evolution on Escherichia coli. We introduced an E. coli strain (lac-), initially unable to utilize lactose due to a frameshift mutation, into two different culture media: one medium (L) containing ample sodium acetate and lactose as carbon sources, and the other medium (G) containing abundant glucose and lactose as carbon sources. After 20 days of experimental evolution, our findings revealed that all L-populations underwent parallel evolution through reverse mutation to utilize lactose (lac+), resulting in a relatively higher fitn

SUBMITTER: Wu H 

PROVIDER: S-EPMC11613857 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature