Maturation and refinement of the maculae and foveae in the Anolis sagrei lizard.

ABSTRACT: The fovea is a pit in the center of the macula, which is a region of the retina with a high concentration of photoreceptor cells, which accounts for a large degree of visual acuity in primates. The maturation of this primate visual acuity area is characterized by the shallowing and widening of the foveal pit, a decrease in the diameter of the rod-free zone, and an increase in photoreceptor cells packing after birth. Maturation occurs concurrently with progressing age, increasing eye size, and retinal length/area. These observations have led to the hypothesis that the maturation of the fovea might be a function of mechanical variables that remodel the retina. However, this has never been explored outside of primates. Here, we take advantage of the Anolis sagrei lizard, which has a bifoveate

SUBMITTER: Wahle MA 

PROVIDER: S-EPMC11614144 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature