Neighborhood Disadvantage and Prostate Tumor Aggressiveness among African American and European American Men.

ABSTRACT:

Background

Studies have identified associations between neighborhood disadvantage (ND), which is more likely to affect African American (AA) individuals, and aggressive prostate cancer. Thus, ND may contribute to prostate cancer disparities. However, it is unknown what ND components drive aggressive disease and whether associations vary by race.

Methods

We evaluated associations between aggressive prostate cancer and four ND metrics-Area Deprivation Index (ADI), validated Bayesian Neighborhood Deprivation Index (NDI), racial isolation (RI) index, and historical redlining, and whether these factors interacted with race, among men with prostate cancer treated at the University of Maryland Greenebaum Comprehensive Cancer Center (2004-2021).

Results

We included 1,458 men

SUBMITTER: Boyle J 

PROVIDER: S-EPMC11614192 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature