Association Between the Development of Sensorineural Hearing Loss and Blood NAD⁺ Levels.

ABSTRACT:

Background

Hearing loss prevalence increases with age, affecting over 25% of the global population aged 60 years or older. The aim of the study was to investigate the association between the development of sensorineural hearing loss (SNHL) and the blood levels of nicotinamide adenine dinucleotide (NAD⁺).

Methods

A single-center, observational study was conducted at Kawagoe Otology Institute in Japan. A total of 80 patients were included and allocated to four groups of 20 patients each: patients aged 50 - 79 years with or without unilateral sudden sensorineural hearing loss (SSNHL), and patients aged ≥ 80 years with or without bilateral age-related hearing loss (ARHL). The distribution of whole-blood NAD⁺ levels was investigated. We also measured oxidati

SUBMITTER: Sakata H 

PROVIDER: S-EPMC11614409 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature