Atypical Presentation of an Ovarian Yolk Sac Tumor in an 80-Year-Old Woman: A Case Report and Review of the Literature.

ABSTRACT:

Introduction

Ovarian yolk sac tumors after the menopause are very rare.

Case presentation

We report an atypical case of yolk sac tumor in an octogenarian woman, who presented to the hospital with anasarca, ascites, toxic syndrome, and an abdominal mass. Serum alpha-fetoprotein (AFP) levels were highly increased (246,720 ng/mL), and malignant cells with positive AFP immunohistochemical expression were detected in a diagnostic paracentesis. The definitive diagnosis was established by histopathological examination of the surgical specimen and immunohistochemical detection of positivity for AFP, glypican 3, cytokeratin AE1/AE3, and focal positivity for SALL4 and CK7. Adjuvant chemotherapy was refused by the patient. Postoperative AFP values decreased to normal limits. One year a

SUBMITTER: Maldonado V 

PROVIDER: S-EPMC11614451 | biostudies-literature | 2024 Jan-Dec

REPOSITORIES: biostudies-literature