Evaluation of a novel forward-looking optical coherence tomography probe for endoscopic applications: an ex vivo feasibility study.

ABSTRACT:

Background

As a result of recent advances in the development of small microelectromechanical system mirrors, a novel forward-looking optical coherence tomography (OCT) probe with a uniquely large field of view is being commercially developed. The aim of this study is to prospectively assess the feasibility of this advanced OCT probe in interpreting ex vivo images of colorectal polyp tissue and to identify necessary steps for further development.

Methods

A total of 13 colorectal lesions from 9 patients, removed during endoscopic resection, were imaged ex vivo with the OCT device and compared with histopathological images that served as the gold standard for diagnostics. Normal tissue from one patient, removed during the endoscopic procedure, was imaged as a negative control.

SUBMITTER: Jacobs FJC 

PROVIDER: S-EPMC11615031 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature