Uptake and Accumulation of Cobalt Is Mediated by OsNramp5 in Rice.

ABSTRACT: Cobalt (Co) contamination in soils potentially affects human health through the food chain. Although rice (Oryza sativa) as a staple food is a major dietary source of human Co intake, it is poorly understood how Co is taken up by the roots and accumulated in rice grain. In this study, we physiologically characterized Co accumulation and identified the transporter for Co²⁺ uptake in rice. A dose-dependent experiment showed that Co mainly accumulated in rice roots. Further analysis with LA-ICP-MS showed Co deposited in most tissue of the roots, including exodermis, endodermis and stele region. Co accumulation analysis using mutants defective in divalent cation uptake showed that Co²⁺ uptake in rice is mediated by the Mn²⁺/Cd²⁺/Pb²⁺ trans

SUBMITTER: Huang H 

PROVIDER: S-EPMC11615428 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature