Comprehensive sex-specific and age-dependent analysis of four-dimensional flow cardiovascular magnetic resonance assessed aortic blood flow-related parameters in normal subjects using single-vendor magnetic resonance systems and single-vendor software.

ABSTRACT:

Background

Aortic blood flow characterization by four-dimensional (4D) flow cardiovascular magnetic resonance (CMR) is increasingly performed in aneurysm research. A limited number of studies have established normal values that can aid the recognition of abnormal flow at an early stage. This study aims to establish additional sex-specific and age-dependent reference values for flow-related parameters in a large cohort of healthy adults.

Methods

Two hundred and twelve volunteers were included, and 191 volunteers completed the full study protocol. All underwent 4D flow CMR of the entire aorta. Quantitative values for velocity, vorticity, helicity, as well as total, circumferential, and axial wall shear stress (WSS) were determined for the aortic root (AoR), ascending aorta (AA

SUBMITTER: Ramaekers MJFG 

PROVIDER: S-EPMC11615600 | biostudies-literature | 2024 Winter

REPOSITORIES: biostudies-literature