ReBiA-Robotic Enabled Biological Automation: 3D Epithelial Tissue Production.

ABSTRACT: The Food and Drug Administration's recent decision to eliminate mandatory animal testing for drug approval marks a significant shift to alternative methods. Similarly, the European Parliament is advocating for a faster transition, reflecting public preference for animal-free research practices. In vitro tissue models are increasingly recognized as valuable tools for regulatory assessments before clinical trials, in line with the 3R principles (Replace, Reduce, Refine). Despite their potential, barriers such as the need for standardization, availability, and cost hinder their widespread adoption. To address these challenges, the Robotic Enabled Biological Automation (ReBiA) system is developed. This system uses a dual-arm robot capable of standardizing laboratory processes within a closed a

SUBMITTER: Koniger L 

PROVIDER: S-EPMC11615785 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature