The landscape of fusion transcripts in plants: a new insight into genome complexity.

ABSTRACT:

Background

Fusion transcripts (FTs), generated by the fusion of genes at the DNA level or RNA-level splicing events significantly contribute to transcriptome diversity. FTs are usually considered unique features of neoplasia and serve as biomarkers and therapeutic targets for multiple cancers. The latest findings show the presence of FTs in normal human physiology. Several discrete reports mentioned the presence of fusion transcripts in planta, has important roles in stress responses, morphological alterations, or traits (e.g. seed size, etc.).

Results

In this study, we identified 169,197 fusion transcripts in 2795 transcriptome datasets of Arabidopsis thaliana, Cicer arietinum, and Oryza sativa by using a combination of tools, and confirmed the translational activity of 150

SUBMITTER: Chitkara P 

PROVIDER: S-EPMC11616359 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature