Zoonotic Potential of Chronic Wasting Disease after Adaptation in Intermediate Species.

ABSTRACT: Chronic wasting disease (CWD) is an emerging disease in Europe. We report an increase in interspecies transmission capacity and zoonotic potential of a moose CWD isolate from Europe after passage in an ovine prion protein-expressing host. Those results indicated some CWD prions could acquire enhanced zoonotic properties following adaptation in an intermediate species.

SUBMITTER: Barrio T 

PROVIDER: S-EPMC11616668 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature