CancerPro: deciphering the pan-cancer prognostic landscape through combinatorial enrichment analysis and knowledge network insights.

ABSTRACT: Gene expression levels serve as valuable markers for assessing prognosis in cancer patients. To understand the mechanisms underlying prognosis and explore potential therapeutics across diverse cancers, we developed CancerPro (https:/medcode.link/cancerpro). This knowledge network platform integrates comprehensive biomedical data on genes, drugs, diseases and pathways, along with their interactions. By integrating ontology and knowledge graph technologies, CancerPro offers a user-friendly interface for analyzing pan-cancer prognostic markers and exploring genes or drugs of interest. CancerPro implements three core functions: gene set enrichment analysis based on multiple annotations; in-depth drug analysis; and in-depth gene list analysis. Using CancerPro, we categorized genes and cancers i

SUBMITTER: Wang Z 

PROVIDER: S-EPMC11616677 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature