The transformation of sensory to perceptual braille letter representations in the visually deprived brain.

ABSTRACT: Experience-based plasticity of the human cortex mediates the influence of individual experience on cognition and behavior. The complete loss of a sensory modality is among the most extreme such experiences. Investigating such a selective, yet extreme change in experience allows for the characterization of experience-based plasticity at its boundaries. Here, we investigated information processing in individuals who lost vision at birth or early in life by probing the processing of braille letter information. We characterized the transformation of braille letter information from sensory representations depending on the reading hand to perceptual representations that are independent of the reading hand. Using a multivariate analysis framework in combination with functional magnetic resonance

SUBMITTER: Haupt M 

PROVIDER: S-EPMC11616995 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature