Associations between non-anaemic iron deficiency and outcomes following elective surgery for colorectal cancer: a prospective cohort study.

ABSTRACT:

Background

Iron deficiency is present in up to 75% of patients presenting for colorectal cancer surgery. It is unclear whether iron deficiency without anaemia is associated with worse postoperative outcomes. We hypothesised that, in adults without anaemia undergoing surgery for colorectal cancer, iron deficiency would be associated with worse postoperative outcomes relative to an iron-replete state.

Methods

We performed a prospective, observational study, recruiting adults (aged ≥ 18 y) without anaemia who were undergoing surgery for colorectal cancer in 16 hospitals across Australia and Aotearoa/New Zealand. Anaemia was defined as a haemoglobin concentration < 130 g.l^-1 for men and < 120 g.l^-1 for women. Iron deficiency was defined primarily as transfe

SUBMITTER: Miles LF 

PROVIDER: S-EPMC11617130 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature