Sedation for awake tracheal intubation: A systematic review and network meta-analysis.

ABSTRACT:

Background

Different sedation regimens have been used to facilitate awake tracheal intubation, but the evidence has not been synthesised robustly, particularly with respect to clinically important outcomes. We conducted a systematic review and network meta-analysis to determine the sedation techniques most likely to be associated with successful tracheal intubation, a shorter time to successful intubation and a lower risk of arterial oxygen desaturation.

Methods

We searched for randomised controlled trials of patients undergoing awake tracheal intubation for any indication and reporting: overall tracheal intubation success rate; tracheal intubation time; incidence of arterial oxygen desaturation; and other related outcomes. We performed a frequentist network meta-analysis fo

SUBMITTER: El-Boghdadly K 

PROVIDER: S-EPMC11617133 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature