Peripheral Perfusion Index in Ugandan Children With Plasmodium falciparum Severe Malaria: Secondary Analysis of Outcomes in a 2014-2017 Cohort Study.

ABSTRACT:

Objectives

Continuous, noninvasive tools to monitor peripheral perfusion, such as perfusion index (PI), can detect hemodynamic abnormalities and assist in the management of critically ill children hospitalized with severe malaria. In this study of hospitalized children with severe malaria, we aimed to assess whether PI correlates with clinical markers of perfusion and to determine whether combining PI with these clinical measures improves identification of children with greater odds of mortality.

Design

Post hoc analysis of a prospective, multicenter, cohort study conducted between 2014 and 2017.

Setting

Two referral hospitals in Central and Eastern Uganda.

Patients

Six hundred children younger than 5 years old with severe malaria and 120 asymptomatic community

SUBMITTER: Boland W 

PROVIDER: S-EPMC11617272 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature