Relationship Between Urinary Uranium and Cardiac Geometry and Left Ventricular Function: The Strong Heart Study.

ABSTRACT:

Background

Uranium is a potentially cardiotoxic, nonessential element commonly found in drinking water throughout the United States.

Objectives

The purpose of this study was to evaluate if urinary uranium concentrations were associated with measures of cardiac geometry and function among American Indian young adults from the Strong Heart Family Study.

Methods

Urinary uranium was measured among 1,332 participants free of diabetes, cardiovascular disease, and <50 years of age at baseline (2001-2003). Transthoracic echocardiography and blood pressure were assessed at baseline and at a follow-up visit (2006-2009). We estimated adjusted mean differences in cardiac geometry and function measures at baseline and follow-up using linear mixed-effect models with a random interc

SUBMITTER: Lieberman-Cribbin W 

PROVIDER: S-EPMC11617505 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature