Moderating effects of body composition biomarkers on the relationship between thyroid hormones and cognitive performance in euthyroid older adults: insights from NHANES data.

ABSTRACT:

Background

Thyroid hormones are essential for cognitive function and can impact cognitive performance even in euthyroid individuals. This study investigates how thyroid hormones influence cognitive performance in the elderly and whether body composition biomarkers moderate this relationship. The aim is to determine if lifestyle interventions should prioritize weight loss, overall body fat reduction, or abdominal fat loss.

Methods

We analyzed data from the NHANES 2011-2012 dataset, focusing on thyroid hormone levels, cognitive performance, and body composition metrics in euthyroid individuals aged 60 to 80 years. A total of 573 participants were included in the analysis. Pearson correlation analyses were conducted to evaluate the associations between thyroid hormone indicator

SUBMITTER: Li X 

PROVIDER: S-EPMC11617516 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature