Mechanisms underlying the low-temperature adaptation of 17β-estradiol-degrading bacterial strain <i>Rhodococcus</i> sp. RCBS9: insights from physiological and transcriptomic analyses.

ABSTRACT: The 17β-estradiol (E2)-degrading bacterium Rhodococcus sp.RCBS9 previously showed remarkable resistance to the combined stresses of low temperature and E2. In this study, physiological experiments and transcriptomic analysis were performed to investigate the mechanisms underlying the strain's low-temperature adaptation and briefly analyze how it maintains its ability to degrade E2 at low temperature. The results showed that the strain's signal transduction functions, adaptive changes in cell membrane and cell wall structure, gene repair functions, and synthesis of antioxidants and compatible solutes are key to its ability to adapt to low temperature. In addition, its stress proteins in response to low temperature were not typical cold shock proteins, but rather universal stress prot

SUBMITTER: Li Q 

PROVIDER: S-EPMC11617531 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature