Abnormal eye movements: relationship with clinical symptoms and predictive value for Alzheimer's disease.

ABSTRACT:

Background

Abnormal eye movements occur at the early stages of Alzheimer's disease (AD). However, the characteristics of abnormal eye movements of patients with AD and their relationship with clinical symptoms remain inconsistent, and their predictive value for diagnosing and monitoring the progression of AD remains unclear.

Methods

A total of 42 normal controls, 63 patients with mild cognitive impairment due to AD (AD-MCI), and 49 patients with dementia due to AD (AD-D) were recruited. Eye movements were assessed using the EyeKnow eye-tracking and analysis system. Cognitive function, neuropsychiatric symptoms, and activities of daily living were evaluated using various rating scales, and correlation analyses and receiver operating characteristic curves were performed.

Re

SUBMITTER: Qi J 

PROVIDER: S-EPMC11617582 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature