Evaluating salivary MMP-8 as a biomarker for periodontal diseases: A systematic review and meta-analysis.

ABSTRACT:

Objective

Periodontitis is the irreversible destructive process of the periodontium and is the major cause of tooth loss in adults worldwide. Diagnosis of early-stage periodontal disease is crucial for improving outcomes, and to this end, the application of indicator biomarkers is gaining interest. One such method involves measuring the level of matrix metalloproteinase-8 (MMP-8). This systematic review and meta-analysis aims to evaluate the salivary MMP-8 level of periodontitis and gingivitis cases compared to healthy controls.

Data

We evaluated all studies that compared different laboratory techniques for measuring salivary MMP-8 levels in periodontitis and gingivitis patients, alongside healthy controls.

Sources

The systematic search was performed on 10 October 202

SUBMITTER: Domokos Z 

PROVIDER: S-EPMC11617734 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature