Nationwide study of chronic codeine use and its impact on cough related diseases in South Korea.

ABSTRACT: Codeine is widely used to control coughs, although concerns about its overuse arise due to its side-effects. This study aimed to evaluate the status of codeine usage according to various medical conditions. The Korean National Health Insurance Service sample cohort was analyzed. Subjects with more than continuous sixty days of antitussive and codeine were defined as chronic users. It was evaluated according to age, smoking status, chronic obstructive pulmonary disease (COPD), asthma, allergic rhinitis (AR), bronchiectasis, chronic cough (CC), gastroesophageal reflux disease (GERD), and lung cancer. A total of 89,289 chronic antitussive users were identified, of whom 589 were chronic codeine users. The chronic codeine users were older, more likely to be smokers, and more likely to have mult

SUBMITTER: An TJ 

PROVIDER: S-EPMC11618306 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature